Seeking extremophiles Recombinant Biocatalysis, Inc.

Phylogeny of Extremophiles

Extreme Environments and Extremophiles

Protein Adaptations in Archaeal Extremophiles

Extremophiles, especially those in Archaea, have a myriad of adaptations that keep their cellular proteins stable and active under the extreme conditions in which they live. Rather than having one basic set of adaptations that works for all environments, Archaea have evolved separate protein features that are customized for each environment. We categorized the Archaea into three general groups ...

BIOTECHNOLOGICALLY RELEVANT ENZYMES AND PROTEINS Immobilised whole-cell recombinant monoamine oxidase biocatalysis

This work demonstrates the first example of the immobilisation of MAO-N whole cells to produce a biocatalyst that remained suitable for repetitive use after 11 months of storage and stable up to 15 months after immobilisation. The production ofEscherichia coli expressing recombinant MAON was scaled up to bioreactors under regulated, previously optimised conditions (10 % DO, pH 7), and the amoun...

Extremophiles and Extreme Environments

Over the last decades, the study of extremophiles has providing ground breaking discoveries that challenge the paradigms of modern biology and make us rethink intriguing questions such as "what is life?", "what are the limits of life?", and "what are the fundamental features of life?". These findings and possibilities have made the study of life in extreme environments one of the most exciting ...